Autism Spectrum Disorder – Stem Cell Injection Therapy

Autism Spectrum Disorder is a neurodevelopmental disorder characterised by deficits in social interaction and communication, limited repetitive behaviours and limited interests. It is a disorder that is mostly recognised in the first three years of life and is seen in every society, culture and all over the world.
According to a study conducted in the USA in 1985, the prevalence rate was 1 in 2,500 children and this rate has increased over time. According to recent studies, this rate is 1 in 68 children.
The diagnosis of Autism Spectrum Disorder can be made by specialists with expert observation and information from the family, taking into account the DSM 5 diagnostic criteria.
The DSM, published by the American Psychiatric Association, covers all psychiatric disorders in both children and adults. The DSM manual also includes the causes of these disorders, statistics on age of onset and gender, predictions on the development of disorders and treatment recommendations.
The Stem Cell team consists of professors with more than 25 years of experience in regenerative medicine and stem cell applications.
Our professors have been successfully applying stem cell therapy for 17 years after a long period of research. We are proud of our case series of over 3000 cases.
The stem cell protocol lasts for 3 days.
On the 1st and 2nd day, we make an injection called Filgtrastim in the arm of our patient, which ‘awakens’ the cells.
On the 3rd day, we process it. Our procedures are performed in a clinical environment
. (Children with autism should come hungry
) Sedation is applied in children with autism.
Local anaesthesia is usually sufficient for other treatments.
Stem cells are obtained from the hip bone or abdominal fat.
The stem cell moves towards the damaged or abnormally functioning cell signals and initiates the repair mechanism. Thus, permanent improvement is achieved.
Since stem cells are taken from the person himself/herself, there is no risk of allergy and rejection. No drugs or substances are added to the stem cell cocktail, so there is no risk of side effects.
Orthobiological products are products obtained from the person’s own blood, bone marrow and fat and used in the regeneration of movement system diseases and other tissues when necessary. They are applications that are thought to prevent wear and deterioration of articular cartilage, meniscus, ligaments, tendons and bones, help repair and support treatment. Orthobiological products contain cells, tissues, growth factors (growth factor, GF) or blood components. They are used to reduce pain and inflammation, stimulate tissue regeneration and improve movement system and musculoskeletal functions.
– Detailed histories of people with a previous diagnosis and report are taken, their rehabilitation status, nutritional status, behavioural disorders that meet the diagnostic criteria according to DSM-V criteria are evaluated.
– Since local anaesthesia will be applied, possible allergies are questioned.
– Conditions preventing the administration of autologous blood, bone marrow and fat products are questioned.
– The procedure is performed under local anaesthesia. In paediatric patients, a sedative agent may be administered by the anaesthetist to relax the patients and reduce the pain associated with the procedure.
– The cell cocktail, which can be obtained from the patient’s abdomen, vein or bone marrow by the specialist physician, is sent to the laboratory immediately after collection.
-Stem cells and orthobiological products are obtained under laboratory conditions.
– The patient is positioned for injection.
– The injection site is cleaned.
– Orthobiological products obtained from your own blood, bone marrow and fat are injected by the physician into the areas recommended by the physician. At the same time, fluid and other materials can be removed from the relevant cavities.
– During these procedures, auxiliary techniques such as ultrasonography and EMG can also be used if the doctor deems necessary.
– All of these applications are performed on the same day.
What are the risks of injection procedures?
– Pain, bleeding and numbness at the injection site, temporary skin discolouration, bruising, whitening (depigmentation), muscle wasting (atrophy), tendon and ligament rupture (rupture) may occur.
– In intravenous injections, drugs or blood products may accumulate around the vein and under the skin as the needle leaves the vein. Intravenous clot may form. Air can enter the vein. This can lead to the formation of an air plug (embolus). If the embolus travels to the lungs and other organs, permanent damage can occur.
– Temporary or permanent pain, numbness and weakness in the arm or leg may occur as a result of nerve damage caused by the injection.
– Toxic or allergic reactions to the local anaesthetic and allergic shock may develop.
– Nausea, vomiting, dizziness, palpitations, low or high blood sugar and blood pressure may occur.
– During lumbar puncture, which is the process of taking cerebrospinal fluid (CSF) from the waist under surgical conditions, sufficient CSF may not be taken as a result of patient movement. Brain oedema, haemorrhage, abscess, herniation may occur and may result in death.

– Despite the above-mentioned risks, your doctor considers that the injection should be performed for the benefit of you or your patient.
Are there any alternatives to this procedure?
Some drugs, serum, ozone and orthobiologicals can be administered intramuscularly, intravenously, intra-articularly, intradermally and subcutaneously depending on their structure and indications (necessity). However, the recommended injection is the form of administration that your doctor thinks is most effective for you/your child and has the least side effects. If the necessity of administering orthobiological agents has been explained to you but you do not fully understand this, you can ask your doctor again.
What are the situations that may occur if this procedure is not performed?
If the above-mentioned procedures are not performed, your treatment may be interrupted, your recovery may be delayed, and your or your patient’s condition may worsen. In rare cases, it may be life-threatening. Please note that this application is an alternative method and a complete cure (recovery) may not be achieved in chronic disorders and diseases, including ASD.